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This tag is used to refer to mathematical/probabilistic/statistical modeling questions, usually this tag is used to ask about questions that are related with the mathematical formalism of the model instead of the correctness of a specific model in practice.

4 votes
1 answer
2k views

How to mathematically characterize a feedback loop in ODEs?

I have a biological system that exhibits a feedback type of behavior. The diagram is a schematic of the system of ODEs. In this system, the total amount of $x_1, x_2, x_3$ is conserved; however, there …
Paichu's user avatar
  • 513
31 votes
7 answers
6k views

Applications of mathematics in clinical setting

What are some examples of successful mathematical attempts in clinical setting, specifically at the patient-disease-drug level? To clarify, by patient-disease-drug level, I mean the mathematical work …
0 votes
0 answers
115 views

Global stability question for system with a unique locally-asymptotically-stable steady state

I have an ordinary differential system of dimension 3 that contains a locally-asymptotically-stable unique fixed point. Additionally, the system is strictly-positively invariant and bounded. Now, sup …
Paichu's user avatar
  • 513
7 votes
1 answer
447 views

How to study the global stability for this 3D system?

I am studying a biological system (HIV) and arrived at this simplified dynamical system: \begin{align} x_1' &= a_1 + a_2x_2 - a_1x_2 - a_4x_1 - a_5\frac{1+a_6x_3}{1+a_7x_3}x_1\\ x_2' &= a_5\frac{1+a_ …
Paichu's user avatar
  • 513