Questions tagged [mathematical-biology]

Mathematical biology is an interdisciplinary science that uses mathematical methods to study problems arising from biology, the science studying living organisms and ecosystems.

Filter by
Sorted by
Tagged with
2
votes
2answers
60 views

Explain seemingly non-random figures which arise from random Poisson points with normalization

Context Working with some biological datasets it was puzzling to see the patterns like Figure 2 (right) below. The first feeling was, that it corresponds to some biological effects like correlations ...
3
votes
1answer
103 views

The mean value of the reconstruction complexity of a random sequence

This problem is motivated by the problem of reconstructing a genome from the family of its short subwords. Given a word $w$ and a positive integer $k$, let $M_k(w)$ be the family of all subwords of ...
0
votes
0answers
95 views

Proving positive invariance

I need to prove that set $D$(A picture for Set $D$) given by $$D=\{(x,y):0\leq x\leq L_0,~0\leq y\leq X_0,~0\leq x+y \leq R_0\}\subseteq \mathbb{R}_+^2$$ of the system: $$\dot{x}=k_1(R_0-x-y)(L_0-x)-...
6
votes
1answer
199 views

Time of peak of an SIR epidemic

I've learned some classical results on the peak and the attack rate of an idealized epidemic which evolves according to a SIR model $\dot{s} = -\beta\cdot i \cdot s$ $\dot{i} = +\beta\cdot i \cdot s -...
2
votes
1answer
435 views

How to mathematically characterize a feedback loop in ODEs?

I have a biological system that exhibits a feedback type of behavior. The diagram is a schematic of the system of ODEs. In this system, the total amount of $x_1, x_2, x_3$ is conserved; however, there ...
64
votes
3answers
5k views

Should water at the scale of a cell feel more like tar?

The Navier-Stokes equations are as follows, $$\dot{u}+(u\cdot \nabla ) u +\nu \nabla^2 u =\nabla p$$ where $u$ is the velocity field, $\nu$ is the viscosity, and $p$ is the pressure. Some elementary ...
4
votes
2answers
201 views

Approximated solutions of SEIR models

Numerical solutions of the SEIR equations (describing the spreading of an epidemic disease) – or variations thereof – $\dot{S} = - N$ $\dot{E} = + N - E/\lambda$ $\dot{I} = + E/\lambda - I/\delta$ ...
0
votes
0answers
71 views

Genes mirror geography on a torus?

Disclaimer: this is an open-ended, imprecise question, asking for speculation in a topic that I know relatively little about (random matrix theory and principal component analysis). I originally asked ...
12
votes
6answers
1k views

Suggestions for reducing the transmission rate?

What are suggestions for reducing the transmission rate of the current epidemics? In summary, my best one so far is (once we are down to the stay home rule) to discretize time, i.e., to introduce the ...
10
votes
5answers
2k views

mathematical physics without partial derivatives

Remark: All the answers so far have been very insightful and on point but after receiving public and private feedback from other mathematicians on the MathOverflow I decided to clarify a few notions ...
0
votes
1answer
134 views

Conditions to determine sign of real roots

From a delay system, I obtain the following as part of a characteristic equation: $$f(\lambda) = \lambda - a + be^{-c\lambda},$$ where $a, b,$ and $c$ are positive number and $a<b, ac<1$. My ...
5
votes
0answers
419 views

Status of the Salmon Conjecture

The set-theoretic version of the Salmon Conjecture (that is, finding the equations that cut out the fourth secant variety of the Segre embedding of $\mathbb P^3 \times \mathbb P^3 \times \mathbb P^3$ ...
3
votes
1answer
531 views

Proof that dynamical systems with bounded Kolmogorov complexity can't emulate all Turing machines

Motivation: During a discussion with neuroscientists the question arose as to whether the human brain may emulate any Turing machine. If we assume that animal brains may be modelled as deterministic ...
6
votes
1answer
333 views

Sphere packing processes during biological development

Within the context of mathematical biology, a sphere packing problem occurred to me. I must note that unlike the typical sphere packing problems, the variant I consider involves minimising the average ...
30
votes
7answers
5k views

Applications of mathematics in clinical setting

What are some examples of successful mathematical attempts in clinical setting, specifically at the patient-disease-drug level? To clarify, by patient-disease-drug level, I mean the mathematical work ...
16
votes
4answers
1k views

Differential geometry applied to biology

This was originally a question posted here on MathSE. But I'll ask again here to see if I can get some different answers. I'm looking for current areas of research which apply techniques from ...
3
votes
0answers
69 views

conditions for asymptotic comparison to hold

I have the following simple dynamical system: \begin{align} x_1' &= a - f(x_2)x_1\\ x_2' &= bx_1 - cx_2, \end{align} where all parameters and initial conditions are positive. $f(x_2)$ is a ...
7
votes
1answer
317 views

How to study the global stability for this 3D system?

I am studying a biological system (HIV) and arrived at this simplified dynamical system: \begin{align} x_1' &= a_1 + a_2x_2 - a_1x_2 - a_4x_1 - a_5\frac{1+a_6x_3}{1+a_7x_3}x_1\\ x_2' &= a_5\...
9
votes
1answer
911 views

Why did Voevodsky abandon his work on "singletons"?

In an interview (I link the Google translation), Voevodsky talks about how, in the late 2000s, he worked on the problem of "restoring the history of populations according to their modern genetic ...
2
votes
1answer
50 views

Purpose of using a saturable logistic like term

I would like to know what is the purpose of using the term $P\over (k+P)$ in the following. I found it when reading the article found here but it was commonly used in few other related articles . Is ...
1
vote
0answers
277 views

Life. Intermediate stages

My question is pure mathematics when restricted to the cellular automata theory. John von Neumann got the grasp of and defined life. Many years later biologists supported von Neumann's definition of ...
28
votes
4answers
3k views

Algebra and cancer research

Let me start by acknowledging the existence of this thread: Mathematics and cancer research It is well-known that mathematical modeling and computational biology are effective tools in cancer research....
10
votes
2answers
4k views

Applications of algebraic geometry/commutative algebra to biology/pharmacology

Are there applications of algebraic geometry/commutative algebra to biology/pharmacology? It might be that some Gröbner basis technique is used somewhere? I know there are some applications to ...
11
votes
3answers
2k views

Applications of knot theory to biology/pharmacology

What are the applications of knot theory to biology/pharmacology? I guess there should be some, since proteins are quite long and some of their properties are probably related to whether they are ...
25
votes
7answers
6k views

Applications of group theory to mathematical biology (pharmacology)

Are there applications of group theory — broadly, say, representation theory, Lie algebras, $q$-groups, etc — to mathematical biology? In particular, I am interested in applications to pharmacology — ...
29
votes
16answers
7k views

Mathematics and cancer research

What are applications of mathematics in cancer research? Unfortunately, I heard quite little about applications of mathematics, but I heard something about applications of physics, and let me put this ...
33
votes
16answers
8k views

Interesting mathematical topics arising from biology

I've heard that there's a relatively new field of science called mathematical biology. It will certainly apply well known and less known mathematical techniques to the understanding of some biological ...