Let $S_g$ be a closed orientable surface of genus $g>1$.
How can one prove that its mapping class group $\mathrm{Mod}(S_g)$ is not generated by two Dehn twists?
A pair of simple closed curves in $S_g$ may be very complicated (e.g. there are filling pairs of curves, such that they are in minimal position and they divide $S_g$ into discs). Maybe the question is still open, is it?
I also know several results in this direction, such as:
$\mathrm{Mod}(S_g)$ can be generated by two elements -- a product of $2$ Dehn twists and a product of $2g$ Dehn twists
[Wajnryb, Mapping class group of a surface is generated by two elements, 1996]$\mathrm{Mod}(S_g)$ can be generated by two elements, one of which is a Dehn twist
[Korkmaz. Generating the surface mapping class group by two elements, 2004]$\mathrm{Mod}(S_g)$ can be generated by two torsion elements, of order $g$ if $g\ge6$
[Yildiz. Generating mapping class group by two torsion elements, 2020]
Maybe you can share some similar interesting results?