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Let $H_k=\sum_{j=1}^k\frac1j$ be the harmonic numbers. QUESTION. Can you find an evaluation of the following sum? $$\sum_{a=1}^b(-1)^a\binom{n}{b-a}\frac{H_{b-a}}a.$$

The sequence $a_n=\sum_{k=0}^n\binom{n}k^24^k$ is listed on OEIS along with a couple of combinatorial interpretations. What interested me at the moment is the plethora of binomial single-sums for the ...