There is an exact sequence
$$
0 \to \pi^*\Omega_X \to \Omega_{\tilde X} \to i_*\Omega_{E/Z} \to 0,
$$
where $E$ is the exceptional divisor and $i:E \to \tilde X$ is its embedding.
Dualizing it one gets
$$
0 \to T_{\tilde X} \to \pi^*T_X \to i_*T_{E/Z}(E) \to 0.\qquad(*)
$$
On the other hand, since $E = P(N)$ is the projectivization of the normal bundle, one has the relative Euler sequence
$$
0 \to O_E \to p^*N(-E) \to T_{E/Z} \to 0,
$$
where $p:E \to Z$ is the projection. It implies that $p_*T_{E/Z}(E) = N$, hence pushing forward $(*)$ one gets
$$
0 \to \pi_*T_{\tilde X} \to T_X \to j_*N \to 0,
$$
where $j:Z \to X$ is the embedding. Finally, writing down the cohomology long exact sequence for this you can compute $H^i(T_{\tilde X}) = H^i(\pi_*T_{\tilde X})$.