In my research I need to show that the set $$M \mathrel{:=} \{X \in \mathbb{R}^4,X\ge0\}$$ where $$X(t)=(x_1(t),x_2(t),x_3(t),x_4(t))^T$$ is positively invariant with respect to the following system of fractional ordinary differential equations $$D^{\alpha}(x(t))=f(t,x(t))$$ with initial non-negative condition $x(0)=x_0$, where $f$ is nonlinear and continuous.
My question is: how do I show that $M$ is positively invariant with respect to the system given? Any ideas, references are appreciated.