Let $R$ be a valuation ring containing a field $k$, with residue field $F$ and quotient field $K$. Assume $F/k$ is separable. Is $K/k$ separable?
I have convinced myself that (for a positive answer) it is enough to treat the case of a rank one valuation ("height one" in Bourbaki's terminology), with $F=k$ and $K/k$ finitely generated. (Instaed of the latter condition, we may assume $K$ complete).
The answer is yes for a discrete valuation, because then (if $F=k$) the completion of $R$ is isomorphic to $k[[t]]$.