Let $R$ be a finitely generated $\mathbb{Z}$-algebra with an [edit: linear algebraic] action of $G(\mathbb{Z})$ where $G$ is a split simply-connected semisimple group.
Then for any prime $p$ we have a map $R^{G(\mathbb{Z})} \otimes \mathbb{F}_p \rightarrow (R \otimes \mathbb{F}_p)^{G(\mathbb{F}_p)}$. Is this map necessarily surjective for sufficiently large $p$?
Comments: (1) The simply-connectedness assumption may seem weird; it is made to ensure that $G(\mathbb{Z}) \rightarrow G(\mathbb{F}_p)$ is surjective so that there is a map at all.
(2) If $G$ is a finite group, then the answer is yes by an averaging argument.
(3) If $G$ is unipotent, then the answer is no. For example, take $x \mapsto x+1$ acting on $k[x]$; there are many invariants in positive characteristic (Artin-Schreier covers!).