Let $G$ be a locally compact topological group with closed subgroups $H, N$ and $H$ normalizing $N$. Then $H$ acts continuously on $N$ by conjugation. If it will help, assume that $N$ is nilpotent, so that Haar measures on $N$ and all its closed subgroups are unimodular.
If $n \in N$, let $O = O(n)$ be the orbit of $n$ under the action of $H$:
$$O = \{ hnh^{-1} : h \in H \}$$
Then the group action $H\times O \rightarrow O$ is continuous, transitive, and for fixed $n' \in O$, the map $H \rightarrow O$, $h \mapsto hn'h^{-1}$ is open. This implies that $O$ is homeomorphic to the space of left cosets $H/\textrm{Stab } n$ in the quotient topology, where
$$\textrm{Stab } n = H \cap Z_G(n)= \{ h \in H : hnh^{-1} = n\}$$
Thus to talk about the existence of $H$-invariant measures on $O$, it suffices to talk about them on $H/H \cap Z_G(n)$. Standard results about the Haar measures on $H$ and $H \cap Z_G(n)$ give conditions on when such a measure exists.
On the other hand, suppose instead of considering just one orbit, we consider all of them. That is, we consider the space $H \setminus N$ of orbits of $N$ under the action of $H$. I suppose we give this space the quotient topology. Then is there some natural Borel measure on $H \setminus N$, perhaps related in some way to the Haar measures on $H$ and $N$?