Let $X$ be a reasonable smooth scheme over some base $S$. The tangent sheaf $T_X$ is a Lie algebroid, locally free as a $\mathcal{O}_X$ module, and its Universal Enveloping Lie Algebroid $\mathfrak{U}(T_X)$ is the sheaf of differential operators on $X$.
However, when $X$ is not necessarily smooth, for any open $U \subset X$, we could still apply the Universal Enveloping Lie Algebroid construction to $T_X(U)$ and get a presheaf. Is it a sheaf when X is affine? Or the question is: does the Universal Enveloping Lie Algebroid construction commute with localization?
Thank you.