The musical scale of $5$ fifths has good temperament because $3^5$ is quite close to a power of $2$, namely $2^8-3^5=13$, and I suspect that in the subsequent powers of $3$ none is so close to a power of $2$. Analogously, our usual chromatic scale with $12$ notes has good temperament because $3^{12}$ is very close to a power of $2$, namely $3^{12}-2^{19}=7153$.
Does the Diophantine equation $|3^n-2^m|\le 13$ admit a solution with $n>5$?
Does the Diophantine equation $|3^n-2^m|\le 7153$ admit a solution with $n>12$?
A direct inspection of the first $35$ scales of fifths with good temperament shows that any such solution must be $n>10^{18}$.