Kontsevich proved that any Poisson manifold $M$ has a quantisation $\mathcal{O}_\hbar(M)$: an associative algebra recovering the $\mathcal{O}(M)$ with its Poisson bracket by taking $\hbar=0$. Later he and Tamarkin realised that the crucial step in his proof was secretly saying that the little disks $\mathbf{E}_2$ was formal, i.e. $P_2:=\text{H}^*(\mathbf{E}_2)\simeq \mathbf{E}_2$ as operads. This was applied to the $P_2$-algebra of polyvector fields on $M$.
From nlab, a physics heuristic for why 2d things show up is:
it was shown that [...] the Poisson model of a [...] Poisson manifold computes the star product in the deformation quantization [...]. One may think of this relation between the 2d Poisson sigma-model and quantum mechanics = 1d quantum field theory as an example of the Chern-Simons type holographic principle.
Is it currently known how to make this mathematically precise, or another way that gives a satisfying explanation why the construction of $\mathcal{O}_\hbar(M)$ should pass through $\mathbf{E}_2$?