A locally compact quantum group (in the sense of Vaes-Kustermans) consists of the data $(M, \Delta, \varphi, \psi)$ with $M$ a von Neumann algebra, $\Delta: M \to M \overline{\otimes} M$ a normal unital $*$-homomorphism satisfying coassociativity and $\varphi, \psi: M_+ \to [0, \infty]$ normal, semifinite, faithful weights satisfying left and right invariance.
One often writes $M= L^\infty(\mathbb{G})$ and refers to $\mathbb{G}$ as the locally compact quantum group.
The motivating example for the latter notation comes from the situation where $G$ is a locally compact group, $M= L^\infty(G)=L^\infty(G, \lambda)$, $\Delta: L^\infty(G)\to L^\infty(G)\overline{\otimes} L^\infty(G) \cong L^\infty(G\times G)$ given by $\Delta(f)(s,t) = f(st)$ and $$\varphi: L^\infty(G)\to \mathbb{C}: f \mapsto \int_G f d\lambda, \quad \psi: L^\infty(G)\to \mathbb{C}: f \mapsto \int_G fd\rho$$ where $\lambda$ is left Haar measure and $\rho$ is right Haar measure.
However, I see some problems. For example, for a general locally compact group $G$, it need not even be true that $L^\infty(G, \lambda)$ is a von Neumann algebra (acting on $L^2(G, \lambda)$) or it does not even need to be a $W^*$-algebra (if it is a $W^*$-algebra, then it is automatically true that integration is a normal weight). Of course, if $G$ is $\sigma$-compact, then everything works out nicely. So concretely, my question is:
If $G$ is a non $\sigma$-compact locally compact group, how exactly can we view it as a locally compact quantum group? Do we have to re-define $L^\infty(G, \lambda)$ as is usually done in harmonic analysis?