I should be tarred and feathered for not knowing at least the status of the following question.
Question: Let $\Gamma$ be a discrete amenable group. If $\pi:\Gamma \rightarrow B(\mathcal{H})$ is a unitary representation of $\Gamma$ on a separable Hilbert space $\mathcal{H}$, is the von Neumann algebra $\pi(\Gamma)''$ necessarily injective?
Flippantly one imagines that the answer to this question is yes, by Theorem 2.2 of Bekka's paper on amenable representations. But this result only says that the images of group elements are in the centralizer of a non-normal state...it isn't immediately clear why the entire von Neumann algebra should lie in the centralizer of such a state. If one tries to sidestep this by looking at a proof using almost invariant vectors, one is busted by the fact that a representation that is "$H$-amenable" isn't necessarily amenable in Bekka's sense.
EDIT: Makoto's nice answer below provided me with some closure. I'm still worried that I can't see a more or less direct way to this result from Connes's '76 paper on the classification of injective factors. If this paper can, in a more or less direct and self-contained way, be used to resolve the question, please feel free to include another answer.