Let $G$ be a connected Lie Group. We will denote the outer automorphism group of $G$ by $Out(G)$. Consider $\pi_0(Diffeo(G))$, the mapping class group of the underlying manifold of $G$, and the map,
$k:Out(G)\rightarrow \pi_0(Diffeo(G))$
This map is well defined as follows: Given $\phi_1, \phi_2\in Aut(G)$ such that $\phi_1=g\phi_2g^{-1}$, we may construct a path $\alpha: [0,1]\rightarrow G$ such that $\alpha(0)=g$ and $\alpha(1)=e$, the identity in $G$. Then $H(w,t)=\alpha(t)\phi_2(w)\alpha(t)^{-1}$ is an isotopy with $H(w,0)=g\phi_2g^{-1}=\phi_1$ and $H(w,1)=\phi_2$.
Consider the case where $G=T^2$, the $2$-torus. Then $Out(T^2)\cong GL_2(\mathbb{Z})$ and $\pi_0(Diffeo(T^2))\cong Out(\pi_1(T^2))\cong GL_2(\mathbb{Z})$ via the Dehn-Nielsen-Baer Theorem. In this case, $k$ is an isomorphism.
Another case is the $3$-sphere, in which $Out(S^3)\cong 0$ and $\pi_0(Diffeo(S^3))\cong\mathbb{Z}_2$. In this case, $k$ is injective.
Is there a case where $k$ is surjective? If not, what is the obstruction? Moreover, are there higher dimensional examples of the bijective case? It seems that for higher dimensions, the smooth structures may make this problem computationally intractable.