There is a well established theory of embeddings $G/H \to X$ into a normal variety $X$ where $G$ is a reductive group over an algebraically closed field and the image of any Borel $B$ is open in $X$; that standard reference is Knop.
I wonder if there is similar theory when $G$ is replaced by a Kac-Moody group. I'm most interested in the case the group is a loop group.