Hasse principle is known to hold for homogeneous quadratic equations, but fail for some 3- and 4-variable cubics, such as $5x^3+4y^3+3z^3=0$ or $15x^3+10y^3+4z^3+3t^3=0$. These counterexamples are explained by Brauer–Manin obstructions.
It is known that that homogeneous equations in $n\geq 5$ variables of degree $d<n$ defining smooth surfaces do not have Brauer–Manin obstructions [1]. Hence, any such counterexample to the Hasse principle would be very interesting (and would contradict conjectures stating that Brauer–Manin obstructions are the only ones for certain families of equations).
For example, consider family of equations $ax^4+by^4+cz^4+dt^4+es^4=0$ in $n=5$ variables of degree $d=4$. If we order these equations by $|abcde|$, then the first interesting one is the equation $$ x^4 + y^4 + z^4 + t^4 = 36 s^4, $$ which leads to the question in the title. If we order these equations by $|a|+|b|+|c|+|d|+|e|$, then the first interesting one is $$ 7 x^4 + 3 y^4 + 3 z^4 + 3 t^4 = 2 s^4 $$ which is equivalent to $$ 189 x^4 + y^4 + z^4 + t^4 = 54 s^4. $$ Here, by "interesting" I mean that these equations are locally solvable modulo small primes but have no small integer solutions.
My specific question is whether these equations have any integer solutions $(x,y,z,t,s)\neq (0,0,0,0,0)$. My general question is whether there are any techniques for searching large solutions to equations like this better than direct search combined with analysis modulo small integers? Here, by "direct search" I mean trying values of 4 variables and solve the resulting equations in 1 variable. If there are better methods, are they implemented in any computer algebra system, e.g. Magma?
[1] Bjorn Poonen and Jos´e Felipe Voloch. Random Diophantine equations. In Arithmetic of higher-dimensional algebraic varieties (Palo Alto, CA, 2002), volume 226 of Progr. Math., pages 175–184. Birkh¨auser Boston, Boston, MA, 2004. With appendices by Jean-Louis Colliot-Th´el`ene and Nicholas M. Katz.