This question is based on attempting to construct the (homotopy type) of Lie groups using Cobordism Hypothesis style abstract nonsense.
There is an $\infty$-groupoid of smooth, framed manifolds where the isomorphisms are diffeomorphisms, the paths between isomorphisms are isotopies of diffeomorphisms, and so on. There is also a functor from this category of framed manifolds to the $\infty$-category of spaces sending each manifold $X$ to its fundamental $\infty$-groupoid $\Pi_\infty(X)$
Consider pairs consisting of a $\infty$-group $G$ (i.e. the loop space of some classifying space $BG$) acting on a framed manifold $X$ such that the action of $G$ on $\Pi_\infty(X)$ is homotopy equivalent to the canonical action of $G$ on $G$.
There is by construction such a pair for any compact Lie group: $G$ is the homotopy type of the Lie group and $X$ is the Lie group itself acted on the left by $G$ and equipped with the framing coming from acting by the Lie algebra on the right. Are there any other examples?