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I realize that this problem is extremely generic, so I am pessimistic that there may be concrete solutions, but let me try...

Consider a multi-variate polynomial $P(x)$, is it possible to find explicit parametrizations of the regions where $P(x)>0$? By explicit I mean explicit enough so that one could compute (even just numerically) an integral of some function over some of the regions where $P(x)<0$.

I am especially interested in understanding whether the knowledge of the Newton polytope of $P(x)$ helps in any way.

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