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For a topological group $G$, an older term for a map $BG \to BG$ is a "homotopy homomorphism". If $G$ is connected, taking based loops shows that a homotopy class of such a map is the same as a homotopy class of $E_1$-maps $G \to G$.

For a compact connected simple Lie group $G$, the homotopy classes of maps $BG \to BG$ were classified by Stefan Jackowski, James McClure and Bob Oliver: by Theorem 2 of Homotopy Classification of Self-Maps of BG via G-actions all are given by composing a generalised Adams operation with a map induced by a homomorphism $G \to G$.

I am interested in analogous results for the group $G = \mathrm{Top}(d)$ of homeomorphisms $\mathbb{R}^d \to \mathbb{R}^d$ in the compact-open topology:

What is known about the homotopy classes of maps $B\mathrm{Top}(d) \to B\mathrm{Top}(d)$?

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    $\begingroup$ I am not aware of any results on this. $\endgroup$ Commented Oct 25, 2022 at 22:12
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    $\begingroup$ Conjecture: nothing is known. $\endgroup$ Commented Oct 25, 2022 at 22:12

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