$\DeclareMathOperator\Hom{Hom}\DeclareMathOperator\Sh{Sh}\DeclareMathOperator\PSh{PSh}$We know that a presheaf $\mathcal{F}$ on category $ \mathcal{C} $ gives a colimit preasheaf $ \mathcal{F}^{+} $ defined by Čech cohomology, and then we have the following theorem: $ \mathcal{F}^{\sharp} = (\mathcal{F}^{+})^{+} $ is a sheaf and the canonical map induces a functorial isomorphism $ \Hom_{\PSh(\mathcal{C})}(\mathcal{F} , \mathcal{G}) = \Hom_{\Sh(\mathcal{C})}(\mathcal{F}^{\sharp} , \mathcal{G}) $, for all $ \mathcal{G} $ in $ \Sh(\mathcal{C}) $.
My question is, can we can find a functorial isomorphism between $ \Hom_{\PSh(\mathcal{C})}(\mathcal{F}^{+} , \mathcal{G}) $ and $ \Hom_{\Sh(\mathcal{C})}(\mathcal{F}^{\sharp} , \mathcal{G}) $?
And the analogous question for $ \Hom_{\PSh(\mathcal{C})}(\mathcal{F} , \mathcal{G}) $ and $ \Hom_{\Sh(\mathcal{C})}((\mathcal{F}^{\sharp})^{+} , \mathcal{G}) $.