Yes, many.

Here is an example.
Take two different locally compact groups with minimal Hausdorff topologies, say $G_1=\text{PSL}_2(\mathbb{R})$ and $G_2=\text{PSL}_2(\mathbb{Q}_p)$
for some prime $p$ (endowed with their usual topologies, which are minimal by Theorem 5.3 of http://arxiv.org/pdf/1408.4217.pdf),
and take a group $\Gamma$ that injects densely into both, say $\Gamma=\text{PSL}_2(\mathbb{Q})$ (you could also take $\Gamma$ to be a free group here).
Take $T_i$ on $\Gamma$ to be the pull back of the topology of $G_i$.

Note that for each $i=1,2$, the group $G_i$ is the completion (wtr the two sided uniform structure) of $(\Gamma,T_i)$, by the fact that $\Gamma$ is dense and $G_i$ is complete (as it is locally compact).
In particular, $T_1\neq T_2$.

We are left to show that the topologies $T_1$ and $T_2$ are minimal.
Assume that for some $i\in\{1,2\}$, $S\lneq T_i$ is a weaker topology.
Let $H$ be the completion of $(\Gamma,S)$. The map $\Gamma\to H$ extends canonically to $G_i\to H$ and we get by minimality of $G_i$ that $H$ is trivial.
Thus $S$ is trivial.

As a reply to a comment below, note that the groups $G_i$ are necessarily simple: otherwise they would have a weaker (non-Hausdorff) topologies.