A number of seemingly unrelated elementary notions can be defined uniformly with help of (iterated) Quillen lifting property (a category-theoretic construction I define below) "starting" to a single (counter)example or a simple class of morphisms, for example a finite group being nilpotent, solvable, p-group, a topological space being compact, discrete, T4 (normal).
I would like to see more examplees, to help me understand if there is a bigger picture behind.
Let me give the definitions.
For a property $C$ of arrows (morphisms) in a category, define its {\em left and right orthogonals} as
$$ C^\perp := \{ f :\text{ for each }g \in C\ f \,\rightthreetimes\, g \} $$ $$ {}^\perp C := \{ g :\text{ for each }f \in C\ f \,\rightthreetimes\, g \} $$
here $f \,\rightthreetimes\, g$ reads " $f$ has the left lifting property wrt $g$ ", " $f$ is (left) orthogonal to $g$ ", i.e. for $f:A\longrightarrow B$, $g:X\longrightarrow Y$, $f \,\rightthreetimes\, g$ iff for each $i:A\longrightarrow X$, $j:B\longrightarrow Y$ such that $ig=fj$ ("the square commutes"), there is $j':B\longrightarrow X$ such that $fj'=i$ and $j'g=j$ ("there is a diagonal making the diagram commute").
Examples:
In the category Sets of sets the right orthogonal ${}^\perp \{\emptyset \longrightarrow \{*\}\}$ of the simplest non-surjection $\emptyset \longrightarrow \{*\}$ is the class of surjections. The triple left orthogonal $ ((\{\emptyset \longrightarrow \{*\}\}^\perp)^\perp)^\perp$ is the class of functions which split.
The left and right orthogonals of $ \{x_{1},x_{2}\}\longrightarrow \{*\} $, the simplest non-injection, are both precisely the class of injections.
A finite group $H$ is nilpotent iff $H\longrightarrow H\times H$ is in ${}^\perp(\{ 0\longrightarrow G : G\text{ arbitrary} \}^\perp)$
A Hausdorff space $K$ is compact iff $K\longrightarrow \{*\}$ is in ${}^\perp({}^\perp(\{a\}\longrightarrow \{a{<}b\})_{<5})^{\perp})$; here $^\perp(\{a\}\longrightarrow \{a{<}b\})_{<5}$ denotes maps in $^\perp(\{a\}\longrightarrow \{a{<}b\})$ between spaces of size less than 5.
I give more examples in the answers to my own question I posted, as they require some notation.