Any distribution $T$ on the real line has an anti-derivative, i.e. there exists a distribution $S$ such that $$S'=T\tag{$\ast$}.$$ Here is a constructive proof: with a given $T$,
define the distribution $S$ by
$$
\langle S, \phi\rangle_{\mathscr D',\mathscr D }=-\langle T, \psi_\phi\rangle_{\mathscr D',\mathscr D },
\quad \text{with}\quad (\psi_\phi)(x)=\int_{-\infty}^x \phi(t) dt-\chi_0(x)\int_{\mathbb R} \phi(t) dt,
$$
where the function $\chi_0$ smooth, equal to 1 on $[\max\text{supp} \phi,+\infty)$ and equal to $0$ on $(-\infty, \min \text{supp}\phi]$.
This makes sense since the function $\psi_\phi$ is smooth (obvious) and also compactly supported: if $x\ge \max\text{supp} \phi$, then
$$
(\psi_\phi)(x)=(1-\chi_0(x))\int_{\mathbb R} \phi(t) dt=0.
$$
If $x\le \min\text{supp} \phi$, then
$
(\psi_\phi)(x)=-\chi_0(x)\int_{\mathbb R} \phi(t) dt=0.
$
We check now $S'=T$. Indeed we have
$$
\langle S', \phi\rangle_{\mathscr D',\mathscr D }=
-\langle S, \phi'\rangle_{\mathscr D',\mathscr D }
=\langle T, \psi_{\phi'}\rangle_{\mathscr D',\mathscr D }.
$$
We note that $\int_\mathbb R\phi'(t) dt =0$, so that
$
(\psi_{\phi'})(x)=\phi(x)
$
and thus, we find
$$
\langle S', \phi\rangle_{\mathscr D',\mathscr D }=\langle T, \phi\rangle_{\mathscr D',\mathscr D },\quad \text{i.e.}\quad S'=T.
$$
A simple addendum: if $S_1, S_2$ are two antiderivatives, the $S_2-S_1=\text{constant}.$