Consider lattice paths from $(0,0)$ to $(2n,2n)$ with steps $N=(0,1)$ and $E=(1,0)$ avoiding the points $(2i-1,2i-1)$ for all $1\leq i\leq n$. There are Catalan many $C_{2n}=\frac1{2n+1}\binom{4n}{2n}$ distinct paths of this sort (see, for example, Stanley's EC2, Chapter 6).
A natural variation is: enumerate lattice paths (only north and east steps) from $(0,0)$ to $(2n-1,2n-1)$ avoiding the points $(2i,2i)$ for all $1\leq i\leq n-1$. One may engage the method of inclusion-exclusion to compute these numbers. The simplified form becomes $$2^{2n-1}C_{n-1}.$$
QUESTION. Is there a way to derive the latter counting assuming the former?