What are examples of strikingly anomalous phenomena in mathematics, where just one or a rather small number of cases stand out because they don't fit a general pattern?
This is most interesting when the situation considered is very simple and basic, and where the exceptional cases are not merely the lowest-numbered ones.
For: for example, the outer automorphism of the symmetric group S6 $S_{6}$ (which exists for no other Sn$S_{n}$), and the existence of non-standard differentiable structures on ℝ4 $\mathbb{R}^{4}$ (but no other ℝn$\mathbb{R}^{n}$).