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A "nice" category $\mathcal{C}$ should be (for the purposes of this question) locally presentable at a minimum, and maybe a bit more. One might require $\mathcal{C}$ to be (in roughly order of ...

Let $X$ be a scheme. Is the category $QCoh(X)$ of quasi-coherent sheaves on $X$ locally presentable? If so, can we say anything about the $\kappa$ for which $QCoh(X)$ is locally $\kappa$-presentable? (...