I know this question may seem nonsensical at first but let me exlain what i have in mind:
In enriched category theory we define categories enriched over a monoidal category $(\mathcal{V},\otimes, I)$. An enriched category then is given by a set/class of objects $\mathcal C$ and a rule assigning to every pair $X,Y$ of such objects a hom-object $[X,Y]$. Furthermore we define composition and identities using $\otimes$ and $I$, remodelling the definitions of usual category theory.
Now for the question: Can we go the other way around?
Let's stick to internal homs for the beginning: Given a category $\mathcal V$ ; can say what additional data turn a functor $$[-,-]:\mathcal{V}^{\mathrm{op}}\times\mathcal V\to \mathcal V$$ into something like an internal hom?
In the case of $[X,-]$ having a left adjoint $-\otimes X$ for every $X$, these additional data should result in $(\mathcal V,\otimes)$ becomming a closed monoidal category with internal hom isomorphic to $[-,-]$.