Let $R$ be a commutative Noetherian local ring, and $S$ be an $R$-algebra. Let $x_1,\dots,x_t$ be elements, in the maximal ideal of $R$, which is a regular sequence on both $R$ and $S$, and let $I$ be the ideal generated by $x_1, \dots, x_t$. Then, for every $n\ge 1$, $x_1^n, \dots, x_t^n$ is also regular on both $R$ and $S$ and we have an isomorphism $S/(x_1^n, \dots, x_t^n)S \cong \text{Ext}^t_R\left (R/(x_1^n, \dots, x_t^n)R, S \right) $.
Since $\text{H}^t_I(S)\cong \varinjlim_n \text{Ext}^t_R\left (R/(x_1^n, \dots, x_t^n)R, S \right) $, so we have a canonical map $\rho: S/(x_1, \dots, x_t)S \to \text{H}^t_I(S)$.
My question is: When can we say $\rho(1+ (x_1, \dots, x_t)S) \neq 0$?