Given a 4-by-4 array of distinct words, is it possible to scramble the array in four different ways in such a fashion that each possible word-pair appears adjacently in one of the five arrays (the original array along with the four scrambled arrays)?
Notice that among 16 words there are 120 word-pairs, and that each of the five arrays produces 24 adjacencies, so the governing inequality is tight.
Equivalently, we are trying to express the complete graph on 16 vertices as the union of five disjoint subgraphs, each of which is isomorphic to the square-grid-graph with 16 vertices and 24 edges.
As the title of the post suggests, this question is prompted by the “Connections” puzzles that have recently been appearing in the New York Times: see https://www.nytimes.com/games/connections
I’d also be interested in knowing about the $n$-by-$n$ case (with $(n^2+n)/4$ arrays) or the more symmetrical version of the problem with wrap-around adjacency (with $(n^2-1)/4$ arrays) for suitable $n$. I have found a solution to the latter when $n$ is a prime congruent to 3 mod 4; see the comments.