Let $M$ be a manifold of symplectic type (we do not fix a particular symplectic form) and $N \subset M$ a submanifold of half the dimension. Is there a topological obstruction on the pair $(M, N)$ for the existence of a symplectic form on $M$ for which $N$ is Lagrangian?
One idea is that if $N$ is Lagrangian for some symplectic form, then its normal bundle $TM|_N / TN$ is isomorphic to its cotangent bundle $T^*N$. Is that enough to detect a pair $(M, N)$ for which $N$ is never Lagrangian?