In this math.stackexchange question Adam Rubinson asked (I paraphrase):
Given a natural number $r$, what is the least number $n$ such that every strictly increasing sequence of $n$ real numbers has a subsequence $x_1,x_2,\dots,x_r$ of length $r$ whose sequence of differences $x_2-x_1,x_3-x_2,\dots,x_r-x_{r-1}$ is (nonstrictly) monotonic? (E.g., if $r=4$ then $n=7$.)
I can't recall having seen this before, but it seems like a reasonably natural question, so it must be discussed somewhere in the literature. Where?
Edit. I'm not sure the question should be closed as a duplicate, seeing as I posted it as a reference request, and I still don't know where or whether this result appears as a traditional publication.
I would have expected this to be a "classical" problem. It's hard to believe that it's not among the thousands of problems Paul Erdős wrote about.