Let $A \subset \mathbb F_p \setminus \{0\} $ and let $A+1/A = \{x+1/y:x,y \in A\}$.
Question: For fixed $c>0$, if $|A| \geq cp$, is $|A+1/A|$ at least $(1-o(1))p$ when $p \rightarrow \infty$?
Known: This is false for $c<1/4$ according to Seva's comments.
Take $A$ to be $I \cap I^{-1}$ where $I=[1,m]$ and $m=(1/2-\epsilon)p$. It's sure that $A+1/A=A+A$ is not the whole $\mathbb F_p$. The hard part is that $A$ contains $(m/p)^2p(1-o(1))$ elements.
Let $X$ be the indicator function of $\{(x,1/x):x \in \mathbb F_p \setminus 0 \}$, and $Y$ the indicator function of $\{(x,y):x,y \in [1,m]\}$. The size of $A$ is the value of the inner product $\langle X,Y\rangle$.
To compute the inner product, we decompose $Y$ into a sum of Fourier coefficients.
Let $e(x)=\exp(2\pi i x/p)$, and let $K_\omega$ be the $\omega$-th coefficient of the Fourier transform of the indicator function of the interval $[1,m]$, i.e. $K_\omega = \underset{x=1}{\overset{m}{\sum}} e(\omega x)/p$, where $\omega=0,1,2,...,p-1$.
By the Fourier transform on cartesian products, $\langle X,Y\rangle = \underset{\psi=0}{\overset{p-1}{\sum}} \underset{\omega=0}{\overset{p-1}{\sum}} K_\psi K_\omega \langle e(\psi x)e(\omega y),X \rangle $.
Let $I_0$ be the term where $\psi$ and $\omega$ are both $0$, $I_1$ the sum of the terms where exactly one of $\psi$ and $\omega$ is $0$, and $I_2$ the sum of the terms where both $\psi$ and $\omega$ are nonzero. We have $\langle X,Y\rangle = I_0+I_1+I_2$ and $I_0=m^2(p-1)/p^2$.
To estimate $I_1$ and $I_2$, we need to bound the sum of $|K_\omega|$ over nonzero $\omega$. There is $K_\omega=\frac{e(\omega(m+1))-e(\omega)}{e(\omega)-1}/p$. As $|e(\omega)-1|=2\sin(\pi\omega/p)>4\omega/p$ when $0<\omega<p/2$, we have $|K_\omega|<\frac{2p}{4 \omega} /p = 1/2\omega$ when $0<\omega<p/2$. Thus the sum of $|K_\omega|$ over nonzero $\omega$ is $O(\log p)$.
The terms $K_\psi K_\omega \langle e(\psi x)e(\omega y),X \rangle$ appearing in $I_1$ has norm $K_\psi m/p$ when $\psi$ is nonzero or $K_\omega m/p$ when $\omega$ is nonzero, so $I_1=O(\log p)$.
If both $\psi$ and $\omega$ are nonzero, the term $\langle e(\psi x)e(\omega y),X \rangle$ can be estimated by the Kloosterman sum and it's $O(\sqrt{p})$. Summing over all nonzero $\psi$ and $\omega$, we have $I_2=O(\sqrt{p} \log^2 p)$.
Thus $\langle X,Y\rangle = I_0+I_1+I_2 = m^2(p-1)/p^2 + O(\log p)+O(\sqrt{p} \log^2 p) = (m/p)^2p(1-o(1))$.
This shows that the answer is false for any $c<1/4$.