The theory of Clifford algebras gives us an explicit lower bound for the number of linearly independent vector fields on the $n$-sphere, and Adams proved that this is actually always the best possible: there are never more linearly independent vector fields.
More precisely, this gives the following number: if $n+1 = 16^a 2^b c$ with $c$ odd, $0 \leqslant b \leqslant 3$, we get $\rho(n) = 2^b + 8a$ and there are exactly $\rho(n) - 1$ linearly independent vector fields on $S^n$. This lower bound comes by construction of vector fields from Clifford module structures on $\mathbb{R}^{n+1}$, and figuring these out isn't too hard, it follows from the classification of real Clifford algebras with negative definite quadratic form. This is detailed for example in Fibre Bundles by Husemöller; the material comes from the paper Clifford Modules by Atiyah, Bott, Shapiro. This classification hinges on a particular mod 8 periodicity for real Clifford algebras.
Question: How does this description of vector fields on spheres relate to Bott Periodicity in the real case (either for real $K$-Theory, in the form $KO^{n+8} \cong KO^{n}$, or for the homotopy groups of the infinite orthogonal group, $\pi_{n+8}(O) \cong \pi_n(O)$)?
In particular, I'm inclined to think there should be a rather direct relationship: after all, $K$-theory is talking about vector bundles, sections of which are vector fields! Surely the formula for the number of vector fields on spheres should have a concrete interpretation in terms of $K$-theory? The (underlying) mod $8$ periodicities must be linked!
In addition, the result of periodicity mod 8 for Clifford algebras is also often called Bott Periodicity; what is the deeper relationship here? This other post mentions that the periodicity for Clifford algebras relates to the periodicity for complex K-Theory and so it mentions BU and not BO.