Here is a simple polynomial algorithm. 
Transform your outer parallelepiped to the cube $[-1,1]^N$ 
by the affine map
$$A: x \mapsto 2 V^{-1}(x-x_0) - \mathbf{1},$$
where all components of $\mathbf{1}$ are 1 and
$$V = (v_1,v_2,\ldots,v_N).$$
$A$ maps the base $x_1$ of your second parallelepiped  to $\xi_1$ and its spanning vectors $w_1,\ldots,w_N$ become
$$ \omega_k=2 V^{-1} w_k.$$
The second parallelepiped  is inside the first iff for the maximum norm
$$\|\xi_1 + t_1 \omega_1 +\ldots + t_N \omega_N  \|  \leq 1 $$
for all $t_k \in [0,1]$. Because in the extremal cases $t_k \in \{ 0,1 \},$ the condition can  be easily checked componentwise.
For the $m$-th component one just has to check whether the sum of all 
positive   entries of $\xi_{1,m}$  and $\omega_{k,m}$ is $\leq  1$, and
the sum of all 
negative   entries of $\xi_{1,m}$  and $\omega_{k,m}$ is  $\geq -1$.