Let $V$ be a compactly-supported vector field on $\mathbb{R}^2$, whose zeros inside some open neighbourhood of the closed unit disk $\mathbb{D}^2$ are isolated. 

>Does there exist a sequence of vector fields $V_n \in C^\infty \cap W^{1,2}$ on $\mathbb{R}^2$, such that $V_n \to V$ in $W^{1,2}$ and the $V_n$ do not vanish on  $\mathbb{D}^2$?

If we replace the $W^{1,2}$ convergence with $L^2$ convergence, than the answer [is positive][3]. The idea is to push the zeroes out of the disk by composing $V$ with a diffeomorphism which affects a region of very small measure.

[2]:https://mathoverflow.net/a/345652/46290
[3]:https://math.stackexchange.com/a/3439203/104576

[1]:https://math.stackexchange.com/questions/3433870/can-we-approximate-a-vector-field-on-the-plane-with-non-vanishing-vector-fields/3439203#3439203