Ricci flow is an analytic surgery. Prediction and control of cancer invasion Can be done by Ricci flow theory see this paper Ricci Flow and Entropy Model for Avascular Tumor Growth and Decay Control Tijana T. Ivancevic https://arxiv.org/abs/0806.0691 We can apply discrete Ricci flow like Ollivier Ricci flow, to study cancer and tumors https://www.nature.com/articles/srep12323 There are a list of discrete Ricci curvatures which based on we can define Ricci flow. Just we need to know which discrete Ricci curvature on the graph network is suitable for the tumor.