My first question is the following: Q1: Let $X$ be a Banach space. If its dual $X^\*$ is weak* separable, does $X$ admit an infinite-dimensional and separable quotient $X/M$? To the best of my knowledge, the dual $X^\*$ is weak* separable, when $X$ satisfies one of the following: (i) $X$ is separable; (ii) $X$ is the dual of a separable Banach space; (iii) $X$ is Hereditary Indecomposable Banach space. That is, every infinite-dimensional closed subspace of $X$ can not be written as a direct sum of two infinite-dimensional closed subspaces. And, I see that if $X$ satisfies (i) or (ii), $X$ admit an infinite-dimensional and separable quotient. Q2: Is it true that $X$ admit an infinite-dimensional and separable quotient, if $X$ satisfies (iii) ?