This is a problem from page 3 of [the paper][1], the author claim that [![enter image description here][2]][2] > Problem. Let the differential operator $P=-\partial_x^2+W(x)$ be defined on $D(P)=H^2(S^1)\subset L^2(S^1)$, if $W\in L^2(S^1)$, then $P$ is self-adjoint. By definition, $v\in D(P^*)$ if and only if there exists $C(v)>0$ such that $|\langle Pu,v\rangle_{L^2}|\leq C(v)\|u\|_{L^2}$ for all $u\in D(P)$. On the one hand, It is easy to show that $H^2(S^1)\subset D(P^*)$ by integration by parts, on the other hand, if $v\in D(P^*)$, then there exists $P^*v\in L^2(S^1)$ such that for $u\in D(P)$ $$\langle P^*v,u\rangle=\langle v,Pu\rangle =\int_{S^1} v(x)(-\partial^2_xu(x)+W(x)u(x))\,dx,$$ in the sense of distribution, we get $P^*v=-\partial_x^2 v+W(x)v$, so the question is if $v\in L^2(S^1)$ and $-\partial_x^2 v+W(x)v \in L^2(S^1)$, where $-\partial_x^2$ is distributional derivative, how to prove $v\in H^2(S^1)$? If $W\in L^{\infty}(S^1)$, we get the conclusion by elliptic regularity, but how to deal the case of $W\in L^2(S^1)$? [1]: https://arxiv.org/pdf/1301.1282.pdf [2]: https://i.sstatic.net/t2H1Q.png