An example of an important solution to a little-known problem might be
Frank P. Ramsey's "On a problem of formal logic" in Proc. London Math.
Soc. 30 (1930) 264-286. The problem was in logic and not well-known even
to logicians, but Ramsey's solution was taken up by combinatorialists 
(notably Erdős and Szekeres) and it grew into the important field now known as
Ramsey theory.