The following answer attempts to characterize all isometry groups of finite-dimensional normed spaces as essentially the closed subgroups of $O(n)$. Perhaps someone could explain which these are, but I guess they are all "finite modulo Euclidean subspaces". I assume that an isometry is a *bijection* preserving the distance function. By the Mazur-Ulam theorem it then follows that an isometry is a linear transformation composed with a translation. Thus we may assume without loss of generality that an isometry fixes the origin, so the isometry group is a subgroup of $GL(n)$. Then I think the isometry groups of finite-dimensional normed spaces are exactly the conjugates in $GL(n)$ of the closed subgroups of $O(n)$ that contain $-id$. Consider the John ellipsoid $E$ of the unit ball $B$ of some $n$-dimensional normed space. This is the ellipsoid of largest volume contained in $B$ and, crucially, it is the unique such ellipsoid. After some choice of basis we may assume that $E$ is the Euclidean ball. An isometry maps $B$ onto $B$, so it must map the John ellipsoid to the John ellipsoid. It follows that the isometry group is a necessarily closed subgroup of $O(n)$ containing $-id$. I'm not so sure, but conversely, take any closed (hence compact) subgroup $G$ of $O(n)$ containing $-id$. Fix such an orbit $Gv$ by taking $v$ to be a Euclidean unit vector. Then $Gv$ is a compact set of Euclidean unit vectors. Then the convex hull of $Gv\cup -Gv$ is still compact, so gives a unit ball $B_0$ of some norm on the linear span of $Gv$. If this linear span is all of $\mathbb{R}^n$, then hopefully the only isometries are the elements of $G$. If the linear span is not all of $\mathbb{R}^n$, then the unit ball has to be made full-dimensional in a sufficiently rough way, so as not to add any more isometries.