There are plenty of such manifolds, but as Danny indicates in his answer, there is likely not a classification. 

Take any acyclic group $G$ with a finite aspherical 2-complex $C$ with $\pi_1(C)=G$. Then one can create an aspherical 4-manifold with boundary having $G$ as fundamental group. We may assume that the 1-skeleton $C^{(1)}$ of $C$ is a wedge of $k$ circles. Then take a 4-dimensional handlebody $H$ with $k$ 1-handles, with a spine of $C^{(1)}$. There are $k$ disks attached to the 1-skeleton in $C$. Attach $2$-handles to $H$ in such a way that the core of the attaching map is homotopic to the attaching map in the 2-skeleton $C^{(1)}$ to get a manifold $W$ with [handle structure][1] so that $C$ is a deformation retract of $W$, and hence $\pi_1(W)\cong G$. By the [Poincaré-Lefschetz theorem][2], $\partial W$ is a homology 3-sphere. 

To get such groups $G$, one can choose a [small-cancellation][3]
 $C'(\frac16)$ balanced presentation with $H_1(G)=0$. Then a presentation complex $C$ will be aspherical and acyclic. 

The difficulty here is that one has no idea what 3-manifold the boundary of such a manifold will be. Moreover, it's not clear what the homeomorphism classification of such manifolds is, even if they have the same aspherical 2-skeleton spine and boundary. 

Presumably there are also examples which do not have a 2-dimensional spine. 

In the case of empty boundary, there is even less known about the classification, although examples exist. For example, I'm not sure if it's know that $PD(4)$ groups are the fundamental groups of $4$-manifolds. 


  [1]: https://en.wikipedia.org/wiki/Handle_decomposition
  [2]: https://en.wikipedia.org/wiki/Lefschetz_duality
  [3]: https://en.wikipedia.org/wiki/Small_cancellation_theory#Asphericity