**The main references** for this question are **1** : V.Voevodsky's paper [Triangulated categories of motives over a field](https://www.math.ias.edu/vladimir/sites/math.ias.edu.vladimir/files/s5.pdf) **2** : the book "Lecture notes in motivic cohomology" written by Carlo Mazza, Vladimir Voevodsky and Charles Weibel. **Context:** in both **1** and **2** we can find a possible definition of motivic cohomology using $\mathit{Hom}$ in the category of geometric motives over $k$. I begin to recall the main ideas of this. This category looks to be in **1** the pseudo-abelianisation of a localisation of the bounded complexes of smooth schemes over a field $k$, and it is in **2** the same construction, but now on the category of sheaves (of $R$-algebra) with transfers for the Nisnevich site (**questions:** why this particular site? Do we obtain the same category if $R=\mathbb{Z}$?). Then the category of effective Chow motives over $k$ embeds through a functor $M$ into effective geometric motives over $k$ (see proposition 20.1 of **2**). Now, given a smooth scheme $X$ we define as in [**2**, definition **14.16**] the motivic cohomology (for a ring $R$) to be $$H^{n,i}_{\text{mot}}(X,R) \overset{\text{def}}{=}\mathit{Hom}_{\text{geo. motives}}(M(X),R(i)[n]).$$ **My question is:** Are we able to generalize the above construction, replacing $R$ by a sheaf. In particular, I am interested in the case where $R=M$ with $M$ a Chow motive over $X$ seen as a locally constant sheaf over $X$. If the answer is "Yes and it is exactly the same construction" then is there any reference which deals with it? More generally do you have any reference for motivic cohomology of a scheme $X$ with coefficient in a Chow motive over $X$?