Reading Lam's [Introduction to Real Algebra][1], he remarks that: 

 1. For a Dedekind domain $A$ with quotient field $F$, then $s(A)$ is either $s(F)$ or $s(F) + 1$. Furthermore, $s(A)$ is either $\infty$, $2^{n}$ or $2^{n} + 1$ for integers $n \geq 0$. For $n \geq 2$ there are no examples in literature of an $A$ such that $s(F) = 2^n$ and $s(A) = 2^n +1$.
 2. For a regular local ring, the relation between $s(A)$ and $s(F)$ is known(equality) for low dimensions, and he conjectures that this holds for higher dimensions.


As Lam's paper was written in 1984 I was hoping to find out whether there have been any development in respect to these two questions. I have tried searching for it, but haven't found anything related to it.
 
**Background:** The level of a commutative ring, denoted $s(A)$, is the smallest natural number $n$ such that $-1$ can be expressed as a sum of $n$ squares in $A$. if $-1$ is not a sum of squares we define the level of $A$ to be $\infty$.

  [1]: https://projecteuclid.org/journals/rocky-mountain-journal-of-mathematics/volume-14/issue-4/An-introduction-to-real-algebra/10.1216/RMJ-1984-14-4-767.full