This is Cerf's pseudoisotopy implies isotopy theorem. 

Cerf's result is true in high dimensions, while it's independently known in a low-dimensional range.  In dimension 2 it goes back to Earle-Eells result that $\pi_0 Diff(S^2)$ has precise two components, and in dimension $3$ it is the analogous theorem of Cerf.  But I think it's an open problem for n=4. 

Cerf (1970) "La stratification naturelle des espaces de fonctions differentiables reelles et le theoreme de la pseudo-isotopie" Inst. Hautes. Etudes Sci Publ. Math 39 5--173