If laplacian $\Delta_n$ is defined just as $[\Delta_n f](u)=\sum_v (f(v)-f(u))$, where the sum is over all neighbors v of the vertex u, then the answer is NO. Informal reason is that such $\Delta_n$ does not feel the embedding of the graph into the manifold $M$ at all.

More promising approach is to define $\Delta_n$ as $[\Delta_n f](u)=\sum_v c(uv)(f(v)-f(u))$ with some edge weights $c(uv)$ depending on the embedding of the graph into $M$. For right choice of weights the answer is positive in some particular cases: e.g., square lattice in the plane, isoradial triangulation of the plane, regular triangulation of the plane. In general there is no ``natural'' laplacian $\Delta_n$ such that convergence holds.

Here are some references, see also references therein:

[1] M. Wardetzky, S. Mathur, F. Kaberer, E. Grinspun, Discrete Laplace operators: no free lunch, Eurographics Symp. Geom. Processing, A.~Belyaev, M.~Garland (eds.), 2007.

[2] D. Chelkak and S. Smirnov, Discrete complex analysis on isoradial graphs, Adv. Math., to appear, http://arxiv.org/abs/0810.2188v2.

[3] R. Courant, K. Friedrichs, H. Lewy, Uber die partiellen Differenzengleichungen der mathematischen Physik, Math. Ann. 100, (1928), 32--74. Russian transl.: Russ. Math. Surveys 8 (1941), 125--160.