In the short biography article on the Alexander Grothedieck

http://www.ams.org/notices/200409/fea-grothendieck-part1.pdf ,

it is mentioned that after Grothendieck submitting his first thesis on Topological Vector Spaces(TVS), apparently, told Bernard Malgrange that 'There is nothing more to do, the subject is dead.'

Also, after nearly two decades, while listing 12 topics of his interest Grothendieck gives least priority to Topological Tensor Products and Nuclear Spaces.

Now, the questions I have are:
What made Grothendieck make this pronouncement on TVS? Are there no more interesting or significant problems attacked in this area after Grothendieck?

Thank you in advance for your answer.