Someone recently [asked][1] what the epimorphisms in the category of schemes are; the other day I had been wondering about the similar question: what are the monomorphisms in the category of schemes? I am often frustrated working with schemes because, unlike a lot of other categories, it is not immediate that you have left cancellation of morphisms when you know the underlying map on sets is injective--and I think it must not be true in general, though I don't have an example in mind. Are there nice situations or additional conditions that guarantee that one may safely cancel morphisms of schemes on the left? 


  [1]: http://mathoverflow.net/questions/56564/what-are-the-epimorphisms-in-the-category-of-schemes