Here is a question which seems true to me but I can't rigorously show. Suppose $K$ is a compact subset of $\mathbb{R}^n$ such that $\mathbb{R}^n\setminus K$ is connected, does it follow that for any connected open set $U\subset \mathbb{R}^n$ such that $U\supset K$, $U\setminus K$ is also connected?