A short answer is "why not?". A longer answer would be to look at the known examples of non-Hopfian groups and try to make them lacunary hyperbolic. A quite general construction can be found in our paper with Dani Wise (Sapir, Mark; Wise, Daniel T. Ascending HNN extensions of residually finite groups can be non-Hopfian and can have very few finite quotients. J. Pure Appl. Algebra 166 (2002), no. 1-2, 191–202.). See Lemma 3.1 there, in particular. It is quite possible that this construction or its slight modification can be lacunary hyperbolic.
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